The ISOPP Standards are the standards for the safe handling of cytotoxic drugs indicated by the International Society of Oncology Pharmacy Practitioners (ISOPP). I would like to provide a summary regarding the history of the ISOPP Standards based on the foreword. In 2003, efforts to create standards by the ISOPP were begun; however, for their creation, it was necessary to survey and analyze the existing regulations and guidelines as well as standards and recommendations of various regions of the world, and based on 15 documents from a total of 7 countries, including Canada, Germany, and the United States, a database consisting of 29 sections covering everything from the prevention of non-sterile cytotoxic pharmaceuticals and administration errors, patient-related items, and items related to their safe handling during chemotherapy, and then performed analysis and study. Subsequently, in writing the standards, the EudraLex GMP Guideline, which defines regulations relating to pharmaceuticals in the EU (European Union), and alerts (warnings) by the NIOSH (National Institute of Occupational Safety and Health) and guidelines of OSHA (Occupational Safety and Health Administration) in the United States as well as guidelines in Europe, such as those of Germany, Holland, and France, were studied further. A review of the information that was written was also performed by an evaluation team, and in 2007, the current ISOPP Standards were announced after being subject to debate at the 2004 ISOPP Symposium. These standards are best practices based on the latest evidence at the current point in time.
The ISOPP Standards are comprised of 21 sections. When excerpting items and introducing them, topics include transfer of cytotoxic drugs, matters regarding employees, education and training, personal protective equipment, ventilation devices, cleaning methods, washing, handling patient excrement, and in-home care, and almost all the handling techniques that medical personnel who handle cytotoxic drugs should observe are covered.